|
Madoka Akimoto |
Supervisor:
Dr. Giuseppe Melacini
Degree:
PhD
Laboratory:
ABB-A202
E-mail:
akimotm@mcmaster.ca
Phone: ext.
26317
Project
Title: |
|
Silvia Albu |
Supervisor:
Dr. Fred
Capretta
Dr. John
Valliant
Degree:
PhD
Laboratory:
ABB-465E/W
E-mail:
Phone: ext.
26335
Project Title: |
|
Vincent
Azhikannickal |
Supervisor:
Dr. Paul Berti
Degree:
MSc
Laboratory:
ABB-A201
E-mail:
azhikavj@mcmaster.ca
Phone: ext.
27907
Project Title: |
|
Naresh Balachandran |
Supervisor:
Dr. Paul Berti
Degree:
PhD
Laboratory:
ABB-A201
E-mail:
balacn5@mcmaster.ca
Phone: ext.
27907
Project
Title:
|
Xiaoke Chi |
Supervisor:
Dr. David Andrews
Degree:
MSc
Laboratory:
HSC-4H41
E-mail:
Phone: ext.
22050
Project
Title:
|
|
James Dzandzi |
Supervisor:
Dr. John Valliant
Degree:
PhD
Laboratory:
ABB-466
E-mail:
dzandzjp@mcmaster.ca
Phone: ext.
27128
Project
Title:
Dual Isotope
Molecular Imaging of Breast and Prostate Cancer
Molecular imaging (MI) can be used to visualize diseases
like cancer and diabetes non-invasively. This allows
for earlier detection of tumour as well as a more
accurate depiction of a tumour. An emerging area in
nuclear imaging is the monitoring of two radiolabeled
compounds simultaneously (also known as dual isotope
molecular imaging-DIMI). In this method two radiopharmaceuticals
derived from radionuclides that differ in emission
energies are visualized using single photon emission
computed tomography (SPECT) simultaneously.
My project involves the development of two probes
to demonstrate the utility of DIMI for detecting prostate
and breast cancer.
|
|
Patrica
Edem |
Supervisor:
Dr. John Valliant
Degree:
MSc
Laboratory:
ABB-466
E-mail:
edempe@mcmaster.ca
Phone: ext.
27128
Project
Title:
Developing
Molecular Imaging Agents for
Cathepsin B
Awards:
Chemical
Biology Travel Award 2008/09 |
|
Nikolas
Eleftheriou |
Supervisor:
Dr. John Brennan
Degree:
MSc
Laboratory:
ABB-A101/A102B
E-mail:
Elefthn@mcmaster.ca
Phone: ext.
27715
Project
Title:
Sol-gel
derived microarrays for bacterial cells
Awards:
Chemical
Biology Travel Award 2008/09 |
|
Erica Forsberg |
Supervisor:
Dr. John Brennan
Degree:
PhD
Laboratory:
ABB-A101/A102B
E-mail:
helde@mcmaster.ca
Phone: ext.
27715
Project
Title:
Development
of sol-gel bioaffinity chromatography
columns
for high-throughput screening assays using nanoLC-MS/MS
Awards:
2009/2010
NSERC CGSM Recipent
|
|
John Grande |
Supervisor:
Dr. Michael Brook
Degree:
MSc
Laboratory:
ABB-359W/A301
E-mail:
Grandejb@mcmaster.ca
Phone: ext.
27938
Project
Title: |
|
Shan Jiang
|
Supervisor:
Dr. Paul Berti
Degree:
MSc
Laboratory:
ABB-A201
E-mail:
jiangs7@mcmaster.ca
Phone: ext.
27907
Project: |
|
Bonnie Leung
|
Supervisor:
Dr. Adam Hitchock
Degree:
PhD
Laboratory:
ABB-333
E-mail:
leungbo@mcmaster.ca
Phone: ext.
24864
Project:
The biocompatibility
of a material is highly dependent on its surface characteristics.
In particular these properties determine the composition
and biological status of the protein layer which forms
upon initial contact with blood or tissue and which
determines subsequent cellular responses. I use a
synchrotron-based X-ray photoemission electron microscope
(X-PEEM) combined with near-edge X-ray absorption
fine structure (NEXAFS) spectroscopy to quantify and
characterize the amount of protein adsorbed on a model
biomaterial substrate.
Awards:
NSERC CGS
2008/2010 Recipient
Chemical Biology Travel Award 2008/09
Chemical Biology Graduate Student Impact
Award 2008/09
The James
F. Harvey and Helen S. Harvey Travel Scholarship 2008/09
Sir
James Lougheed Award of Distinction 2009-2010
|
|
Meghan McFadden
|
Supervisors:
Dr. John
Brennan
Dr. Murray
Junop
Degree:
PhD
Laboratory:
ABB A101
HSC-4N20A
E-mail:
mcfaddmj@mcmaster.ca
Phone: ext.
27715
22912
Project:
Under
the guidance of Dr. John Brennan and Dr. Murray Junop,
I will be working on a co-supervised project spanning
bioanalytical chemistry and structural biology. The
research project centres on double stranded repair
proteins, which will be targets for developing LC/MS
based methods for small molecule screening using sol-gel
derived bioaffinity columns. Once ligands are identified,
X-ray crystallography will be used to generate co-crystal
structures of the proteins and a selection of bound
ligands. Such studies could ultimately lead to the
development of potent and selective anti-cancer therapeutics
Awards:
OGS 2009/2010
Recipient
Chemistry Teaching Assistant
Award 2008/09
|
|
Julijana
Milojevic |
Supervisor:
Dr. Giuseppe Melacini
Degree:
PhD
Laboratory:
ABB-A202
E-mail:
milojej@mcmaster.ca
Phone: ext.
26317
Project:
Awards:
2009/2010
NSERC CGSD2 Recipent
Chemical
Biology Graduate Student Impact Award 2008/09
The Allan
Jackson Ontario Grduate Scholarship 2008/09 |
Vladimir
Popovic
|
Supervisor:
Dr. Paul Berti
Degree:
MSc
Laboratory:
ABB-A201
E-mail:
popovv@mcmaster.ca
Phone: ext.
27907
Project
Title:
Synthesis
and characterization of transition state inhibitors
for the bacterial sialic acid synthase, NeuB.
|
|
Rajeevan
Selvaratnam |
Supervisor:
Dr. Giuseppe Melacini
Degree:
PhD
Laboratory:
ABB-A201
E-mail:
selvarr@mcmaster.ca
Phone: ext.
26137
Project
Title:
Investigation of structural
and dynamial basis of allostery in cyclic-nucleotide
binding proteins by Nuclear Magnetic Resonance Spectroscopy |
|
Meera Shanmuganathan |
Supervisor:
Dr. Philip Britz-McKibbon
Degree:
MSc
Laboratory:
ABB-205W
E-mail:
shanmm2@mcmaster.ca
Phone: ext.
26337
Project
Title: |
Mohini Singh |
Supervisor:
Dr. James McNulty
Degree:
MSc
Laboratory:
ABB-467E/W
E-mail:
singhm6@mcmaster.ca
Phone: ext.
26336
Project
Title: |
Anne Marie
Smith |
Supervisor:
Dr. John Brennan
Degree:
MSc
Laboratory:
ABB-B104
E-mail:
smithame@mcmaster.ca
Phone: ext.
27715
Project
Title: |
|
Alan Vanderkooy |
Supervisor:
Dr. Michael Brook
Degree:
MSc
Laboratory:
ABB-359W/A301
E-mail:
vandea32@mcmaster.ca
Phone: ext.
27938
Project
Title:
Attempts
to use gold nanoparticles for detection
|
|
Lisa Walter |
Supervisors:
Dr. Fred
Capretta &
Dr. Geoff
Werstuck
Degree:
PhD
Laboratory:
ABB-465
E-mail:
waltel@mcmaster.ca
Phone: ext.
26335
Project
Title:
With
the Co-Supervision of Dr. Capretta and Dr. Werstuck,
I am currently studying the enzyme L-glutamine: d-fructose-6-phosphate
amidotransferase, GFAT, a protein of interest in hexosamine
induced insulin resistance in diabetes. GFAT catalyzes
the reaction of L-glutamine and fructose-6-phosphate
to form L-glutamate and glucosamine-6-phosphate. Currently,
I am developing an assay which measures the rate of
glucosamine-6-phosphate formation from GFAT. This
assay will ultimately be used to study potential inhibitory
properties of a library of small molecules
|
|
Morgan Wyatt
|
Supervisor:
Dr. Nathan Magarvey
Degree:
PhD
Laboratory:
HSC 4N53
E-mail:wyattam@mcmaster.ca
Phone: ext
22188
Project
Title:
Characterization
of Natural Products Produced by Nonribosomal Peptide
Synthetases
Awards:
Chemical
Biology Travel Award 2008/09
|
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